The CACTUs Lab

Korte, C., Friedberg, R.D., Wilgenbusch, T., Paternostro, J.K., Brown, K., Kakolu, A., Tiller-Ormord, J., Baweja, R., Cassar, M., Barnowski, A., Movahedi, Y., Kohl, K., Martinez, W., Trafalis, S., & Leykin, Y. (In press). Intolerance of uncertainty and health-related anxiety amid the COVID-19 pandemic: Understanding and weathering the current storm. Journal of Clinical Psychology in Medical Settings.
Moskowitz, J. T. , Addington, E. L., Shiu, E, Bassett, S. M., Schuette, S., Kwok, I., Grote, V. , Freedman, M. E., Leykin, Y., Saslow, L.R., Cohn, M.A, & Cheung, E. O. (In Press). Do facilitator contact, discussion boards, or virtual badges increase adherence to an online self-guided positive psychological intervention for depression? A randomized controlled trial. Journal of Medical Internet Research.
Muñoz, R. F., Pineda, B. S., Barrera, A. Z., Bunge, E., & Leykin, Y. (2021). Digital Tools for Prevention and Treatment of Depression: Lessons from the Institute for International Internet Interventions for Health. Clínica y Salud, 32, 37-40. https://doi.org/10.5093/clysa2021a2
*Bharat, V., Bunge, E. L., Barrera, A. Z. & Leykin, Y. (2021). Emotional Well-Being of Information Technology Professionals Working in India. Journal of Indian Mental Health, 8(2), 140-147.
*Goodmann, D., *Daouk, S., *Sullivan, M., Liu, N. H., Garza, M., Barakat, S., Muñoz, R. F., & Leykin, Y. (2021). Factor analysis of depression symptoms across five broad cultural groups. Journal of Affective Disorders, 282, 227-235. https://doi.org/10.1016/j.jad.2020.12.159.
Muñoz, R. F., Leykin, Y., Barrera, A. Z., Dunn, L. B., Gutierrez, R., *Curland, R. A., Pineda, B. S. (2021). Who comes to a self-help depression prevention website? Characteristics of Spanish- and English-speaking visitors. Internet Interventions, 23, 100359. https://doi.org/10.1016/j.invent.2020.100359.
*Daouk, S., Awaad, R., Maklad, S., Ahmed, B., Barakat, S., Muñoz, R. F., & Leykin, Y. (2021). Common and country-specific characteristics associated with suicidality in the Arab region. Journal of Clinical Psychiatry, 82(1), 19m13199. https://doi.org/10.4088/JCP.19m13199
Stephens, T. N., *Tran, M. M., Bunge, E. L., Liu, N. H., Barakat, S., Garza, M. Leykin, Y. (2020). Children and adolescents attempting to participate in a worldwide online depression screener. Psychiatry Research, 22(7), 291, 113250. https://doi.org/10.1016/j.psychres.2020.113250
Lungu, A., Jun, J. J., Azarmanesh, O., Leykin, Y., Chen, C. E. (2020). Effectiveness of a blended CBT intervention for depression and anxiety in real world settings. Journal of Medical Internet Research, 22(7), e18723. DOI: 10.2196/18723
Bond, M. H., Bunge, E. L., Barrera, A. Z., Leykin, Y., Wickham, R. E., Barlow, M. R., Ceja, A. M., Muñoz, R. F. (2020) Development and Usability of a Spanish/English Smoking Cessation Website: Lessons Learned. mHealth. Epub, http://dx.doi.org/10.21037/mhealth-19-255
*Curland, R. A., *Tran, M. M., *Barba, F, & Leykin, Y. (2020). Depressed individuals’ reasons for and against trying to get better. Clinical Psychologist. Epub. https://doi.org/10.1111/cp.12211
*Bharat, V., Habarth, J., Keledjian, N., & Leykin, Y. (2020). Association between subjective social status and facets of depression self-stigma. Journal of Community Psychology, 48(3), 1059–1065. https://doi.org/10.1002/jcop.22314
*Tran, M. M., *Curland, R., A. & Leykin, Y. (2020). The association between personal knowledge of individuals with emotional or mental problems on treatment-seeking. Psychiatric Services, 71(4), 393-396. https://doi.org/10.1176/appi.ps.201900190
*Spangler, D. A., Muñoz, R. F., Chu, J., & Leykin, Y. (2020). Perceived utility of the Internet-Based Safety Plan in a sample of Internet users screening positive for suicidality. Crisis, 41(2), 146-149. doi: 10.1027/0227-5910/a000600.
*Spangler, D. A., Muñoz, R. F., Chu, J., & Leykin, Y. (2019). Utilization of an automated Internet-based Safety Plan. Journal of Technology in Behavioral Science, 5, 129-138. https://doi.org/10.1007/s41347-019-00120-y
Siev, J., Lit, K., Leykin, Y. (2019). Perceived Decision-Making Styles Among Individuals with Obsessive-Compulsive and Hoarding Disorders. Journal of Obsessive-Compulsive and Related Disorders. Epub. https://doi.org/10.1016/j.jocrd.2019.100472
Addington, E. L., Cheung, E. O., Bassett, S. M., Kwok, I., Schuette, S. A., Shiu, E., Yang, D., Cohn, M., Leykin, Y., Saslow, L. R., Moskowitz, J. T. (2019). Feasibility and enhancement of an online intervention to improve emotion regulation in people with elevated depressive symptoms. Journal of Affective Disorders, 257, 352-364. https://doi.org/10.1016/j.jad.2019.07.049
Dickter, B., Bunge, E. L., Brown, L., Leykin, Y., Furay, E. E., Van Voorhees, B., Marko, M., Gladstone, T. (2019). Impact of an online depression prevention intervention on suicide risk factors for adolescents and young adults. mHealth, 5, 11. https://doi.org/10.21037/mhealth.2019.04.01
Kaplan, C. P., Siegel, A., Leykin, Y., Palmer, N. R., Borno, H., Bielenberg, J., Livaudais-Toman, J., Ryan, C., Small, E. J. (2018). A bilingual, Internet-based, targeted advertising campaign for prostate cancer clinical trials: Assessing the feasibility, acceptability, and efficacy of a novel recruitment strategy. Contemporary Clinical Trials Communications, 12, 60-67. doi: 10.1016/j.conctc.2018.08.005.
Cheung, E. O, Addington, E. L., Bassett, S. M., Schuette, S. A., Shiu, E. W., Cohn, M. A., Leykin, Y., Saslow, L. R., Moskowitz. J. T. (2018). A Self-Paced, Web-Based, Positive Emotion Skills Intervention for Reducing Symptoms of Depression: Protocol for Development and Pilot Testing of MARIGOLD. JMIR research protocols 7(6), e10494. doi: 10.2196/10494.
Bunge, E., Cook, H. M., Bond, M., Williamson, R. E., Cano, M., Barrera, A. Z., Leykin, Y., Muñoz, R. F. (2018). Comparing Amazon Mechanical Turk with unpaid internet resources in online clinical trials. Internet Interventions, 12, 68-73. https://doi.org/10.1016/j.invent.2018.04.001
*Naushad, N., Dunn, L. B., Muñoz, R. F., Leykin, Y. (2018). Depression increases subjective stigma of chronic pain. Journal of Affective Disorders, 229, 456-462. https://doi.org/10.1016/j.jad.2017.12.085
*Gill. S. K., Muñoz, R. F., Leykin, Y. (2018). The influence of perceived stress and depression on suicide-related beliefs in Caucasian and Indian adults. Crisis, 39(2), 127-136. doi: 10.1027/0227-5910/a000492.
Beard, C. L., Stephens, T. N., Bunge, E. L., Leykin, Y., Muñoz, R. F. (2017). Mood management effects of a brief behavioral activation internet intervention. Journal of Technology in Behavioral Science, 2, 163-170. https://doi.org/10.1007/s41347-017-0026-2
Leykin, Y., Dunn, L. B., Muñoz, R. F. (2017). The effect of depression on the decision to join a clinical trial. Journal of Consulting and Clinical Psychology, 85(7), 751-756. doi: 10.1037/ccp0000212
*Elefant, A., Contreras, O., Bunge, E. L., Muñoz, R. F., Leykin, Y. (2017). Micro-interventions produce immediate, but not lasting benefits in mood and distress. Internet Interventions, 10, 10-14. doi: 10.1016/j.invent.2017.08.004.
Muñoz, R. F., Leykin, Y., Barrera, A. Z., Torres, L. D., Brown, C. H., Bunge, E. L. (2017). The impact of phone calls on follow-up rates in an online depression prevention study. Internet Interventions, 8, 10-14. https://doi.org/10.1016/j.invent.2017.02.001
*Rutter, T. M., *Gross, M. S., Barakat, S., Dilley, J. W., Muñoz, R. F., & Leykin, Y. (2016). Sexual orientation and help-seeking for symptoms of depression. Journal of Affective Disorders, 206, 87-93. doi: 10.1016/j.jad.2016.07.003
Bunge, E.L., Williamson, R. E., Cano, M., Leykin, Y., Muñoz, R. F. (2016). Mood management effects of brief unsupported Internet interventions. Internet Interventions. 5, 36-43. https://doi.org/10.1016/j.invent.2016.06.001
Kaplan, C. P., Nápoles, A. M., Narine, S., Gregorich, S., Livaudais-Toman, J., Nguyen, T., Leykin, Y., Roach, M., Small E. J. (2015). Knowledge and attitudes regarding clinical trials and willingness to participate among prostate cancer patients. Contemporary Clinical Trials, 45(Pt B), 443-448. doi: 10.1016/j.cct.2015.09.023.
Aguilera, A., Schueller, S. M., Leykin, Y. (2015). Daily mood ratings via text message as a proxy for clinic based depression assessment. Journal of Affective Disorders, 175(1), 471-474. doi: 10.1016/j.jad.2015.01.033.
Muñoz, R. F. Sorensen, J. L., Areán, P. A., Lieberman, A., Fields, A., Gruber, V. A, Hall, S. M, Kramer, J. M., Leykin, Y. McBurnett, K., McQuaid, J. R., Pfiffner, L. J., Prochaska, J. J., Scheidt, S. D., Shumway, M., Tsoh, J. Y., van Horn, P., Sosa, H., & McNiel, D. E. (2015). Scientist–practitioner training at the internship and postdoctoral level: reflections over three decades. Training and Education in Professional Psychology, 9(2), 105–112. https://doi.org/10.1037/tep0000058
Liu, N. H., *Contreras, O., Muñoz, R. F., & Leykin, Y. (2014). Assessing suicide attempts and depression among Chinese speakers over the internet. Crisis, 35(5), 322-329. doi: 10.1027/0227-5910/a000261.
Leykin, Y., Muñoz, R. F., *Contreras, O., *Latham, M. D. (2014). Results from a trial of an unsupported internet intervention for depressive symptoms. Internet Interventions, 1(4), 175-181. doi: 10.1016/j.invent.2014.09.002
*Gill, S., *Contreras, O., Muñoz, R. F., & Leykin, Y. (2014). Participant retention in an automated online monthly depression rescreening program: patterns and predictors. Internet Interventions, 1(1), 20-25. doi: 10.1016/j.invent.2014.02.003.
*Gross, M. S., *Liu, N. H., Muñoz, R. F., *Contreras, O., & Leykin, Y. (2014). Using Google AdWords for international multilingual recruitment to health research websites. Journal of Medical Internet Research, 16(1), e18. doi: 10.2196/jmir.2986.
Leykin, Y., Aguilera, A., Pérez-Stable, E. J., & Muñoz, R. F. (2013). Prompting depression treatment seeking among smokers: A comparison of participants from six countries in an internet stop smoking RCT. Journal of Technology in Human Services, 31(3), 238-247. doi: 10.1080/15228835.2013.812502.
Schueller, S. M., Leykin, Y., Pérez-Stable, E. J., & Muñoz, R. F. (2013). Selection of intervention components in an Internet Stop Smoking participant preference trial: Beyond randomized controlled trials. Psychiatry Research, 205(1-2), 159-64. doi: 10.1016/j.psychres.2012.08.030
Geraghty, A. W. A., Torres, L. D., Leykin, Y., & Muñoz, R. F., (2013). Understanding attrition from international internet health interventions: A step towards global eHealth. Health Promotion International, 28(3), 442-452. 10.1093/heapro/das029.
Fisher, C. E., Dunn, L. B., Christopher, P, P., Holzheimer, P. E., Leykin, Y., Mayberg, H. S., Lisanby, S., H., Appelbaum, P. S. (2012). The ethics of research on deep brain stimulation for depression: decisional capacity and therapeutic misconception. Annals of the New York Academy of Science, 1265(1), 69-79. doi: 10.1111/j.1749-6632.2012.06596.x.
Muñoz, R. F., Aguilera, A., Schueller, S. M., Leykin, Y., & Pérez-Stable, E. J. (2012). From online randomized controlled trials to participant preference studies: Morphing the San Francisco Stop Smoking site into a worldwide smoking cessation resource. Journal of Medical Internet Research, 14(3), e64. doi: 10.2196/jmir.1852.
Aguilera, A., Leykin, Y., Adler, N. E., & Muñoz, R. F. (2012). Assessing the impact of relative social position and absolute community resources on depression and obesity among smokers. American Journal of Community Psychology, 50(0), 211-6. doi: 10.1007/s10464-012-9492-z
Leykin, Y., Thekdi, S. M., Shumay, D. M., Muñoz, R. F., Riba, M., & Dunn, L. B. (2012). Internet interventions for improving psychological well-being in psycho-oncology: Review and recommendations. Psycho-Oncology. 21(9), 1016-25. doi: 10.1002/pon.1993.
Muñoz, R. F., Beardsley, W. R., & Leykin, Y. (2012). Major depression can be prevented. American Psychologist, 67(4), 285-292. doi: 10.1037/a0027666
Christopher, P. P., Leykin, Y., Appelbaum, P. S., Holtzheimer, P. E., Mayberg, H. S., & Dunn, L. B. (2012). Enrolling in deep brain stimulation research for depression: Influences on decision making. Depression and Anxiety, 29(2), 139-46. doi: 10.1002/da.20916.
Hilton, J. F., Barkoff, L., Chang, Olivia, Ratanaeongsa, N., Sarkar, U., Leykin, Y., Muñoz, R. F., Thom, D. H., & Kahn, J. A. (2012). A cross-sectional study of barriers to personal health record use among patients attending a safety-net clinic. PLoS One, 7(2), e31888. https://doi.org/10.1371/journal.pone.0031888
Leykin, Y., Muñoz, R. F. & *Contreras, O. (2012). Are consumers of Internet health information “cyberchondriacs”? Characteristics of 24,965 users of a depression screening site. Depression and Anxiety, 29(1), 71-77. doi: 10.1002/da.20848
Leykin, Y., Aguilera, A., Torres, L. D., Pérez-Stable, E. J., & Muñoz, R. F. (2012). Interpreting the outcomes of automated Internet-based trials: Example of an international smoking cessation study. Journal of Medical Internet Research, 14(1), e5. doi: 10.2196/jmir.1829.
Leykin, Y., Christopher, P. P. Holtzheimer, P. E., Appelbaum, P. S., Mayberg, H. S., Lisanby, S. H., & Dunn, L. B. (2011). Participants’ perceptions of deep brain stimulation research for treatment-resistant depression: Risks, benefits, and therapeutic misconception. AJOB Primary Research. 2(4), 33-41. doi: 10.1080/21507716.2011.627579
Leykin, Y., Weingardt, K, R. & Cucciare, M. A. (2011). Differential effects of online training on job-related burnout among substance abuse counselors. Journal of Substance Use, 16(2), 127-135. DOI: 10.3109/14659891.2010.526168
Leykin, Y., Aguilera, A., Torres, L. D., & Muñoz, R. F. (2011). Factor structure of CES-D delivered on the Internet in Spanish and English. Psychiatry Research, 185(1-2), 269-274. DOI: 10.1016/j.psychres.2010.04.056
Leykin, Y., *Roberts, C. S., & DeRubeis, R. J. (2011). Decision-making and depressive symptomatology. Cognitive Therapy & Research, 35(4), 333-341. DOI: 10.1007/s10608-010-9308-0
Muñoz, R. F., Cuijpers, P., Smit, P. Barrera, A. Z., & Leykin, Y. (2010). Prevention of major depression. Annual Review of Clinical Psychology, 6, 181-212. DOI: 10.1146/annurev-clinpsy-033109-132040
Leykin, Y. & DeRubeis, R. J. (2010). Decision-making styles and depressive symptomatology. Judgment and Decision Making, 5(7), 506-515.
Leykin, Y. & DeRubeis, R. J. (2009). Allegiance in psychotherapy outcome research: Separating association from bias. Clinical Psychology: Science and Practice, 16(1), 54–65. https://doi.org/10.1111/j.1468-2850.2009.01143.x
Leykin, Y., DeRubeis, R. J., Shelton, R. C., & Amsterdam, J. D. (2007). Changes in patients’ beliefs about the causes of their depression following successful treatment. Cognitive Therapy and Research. 31(4), 437-449. https://doi.org/10.1007/s10608-007-9130-5
Leykin, Y., DeRubeis, R. J., Gallop, R, Amsterdam, J. D., Shelton, R. C., & Hollon, S. D. (2007). The relation of patients’ treatment preferences to outcome in a randomized clinical trial. Behavior Therapy. 38(3), 209-217. DOI: 10.1016/j.beth.2006.08.002
Leykin, Y., Amsterdam, J. D., DeRubeis, R. J., Gallop, R., Shelton, R. C., & Hollon, S. D. (2007). Progressive resistance to SSRI therapy but not to cognitive therapy in the treatment of moderate to severe major depressive episode. Journal of Consulting and Clinical Psychology. 75(2), 267-76. DOI: 10.1037/0022-006X.75.2.267
Neylan, T. C., Lenoci, M. A., Maglione M. L., Rosenlicht, N. Z., Leykin, Y., Metzler, T. J., Schoenfeld, F. B., & Marmar, C. R. (2003). The effect of nefazodone on subjective and objective sleep quality in post-traumatic stress disorder. Journal of Clinical Psychiatry. 64(4), 445-50. DOI: 10.4088/jcp.v64n0415

Welcome to the Choice-making And Computer Technology for Unipolar depression (CACTUs) Lab!

Palo Alto University

What we do

Decision-making of individuals with depression

Internet-based resources for depression

Other topics

The Team

Current members

Alumni

Faculty

Our Projects

Lab projects

BetterBET

Mood Screener

Ultimatum Game

Student-led projects

BetterBET gamification

Lead: Alex Curland

Effect of depression on eyewithess identification

Lead: Jamie Giglio

Determination of capacity to stand trial

Lead: Erica Hamlin

Decision-making of former foster care youth

Lead: Megan Sullivan

Treatment seeking for depression in the Arab region

Lead: Sariah Daouk

Adapting microinterventions for India

Lead: Kalpana Sundaram

Psycho-education intervention for Asian Americans

Lead: Kaylin Jones

Improving perceptions of Special Ed students

Lead: Eunice Magat

Enhancing suicide models with self-discrepancy theory

Lead: Eric Uhl

Using serious games therapeutically

Lead: Hillary Kingman

Understanding the decision to pursue ECT

Lead: Hayley Raybin

Past Projects

Micro-inverventions for sexual assault survivors

Lead: Danni Goodmann

Perception of depression treatment among Russians and Americans

Lead: Anna Freedland

Planned transition in a student therapy clinic

Lead: Chelle Tran

Representation of minorities in stories

Lead: Felipe Barba

Juror Decision-Making

Lead: Bethany Young

Internet-Based Safety Plan

Lead: Danielle Spangler

Mental Health among Indian IT Professionals

Lead: Vidya Bharat

Decisions about depression treatment in Latin America

Lead: Ashley Elefant

Does depression influence decisions about joining clinical trials?

Depression Management Course

MINT: Mood-Improving Internet Tools

Treatment Decisions

Acknowledgements

Funders

Assistants

Collaborators

Publications

You can request publications below* = student or research assistant from the CACTUs lab

Request papers

If you are interested in any of these publications, please write to us using the form below.

Address

Contacts

Welcome to the
Choice-making And Computer Technology for Unipolar depression (CACTUs) Lab!

You can request publications below

* = student or research assistant from the CACTUs lab